SERUM 44™ · The Platform
One platform. Two experiences.
SERUM 44 is one regenerative aesthetics platform expressed in two distinct formulations — a premium at-home serum and a professional clinic formulation.
ConsumerH = Home
SERUM 44-H
At-home regenerative skin serum.
30 mL · Available
Daily continuity. An at-home regenerative skin serum designed for daily skin support and continuity between professional aesthetic experiences — the home expression of the SERUM 44 platform.
- Daily at-home skin support
- Lightweight concentrated serum
- Continuity between professional sessions
- Pairs with PRIVÉE EXOCREAM
ProfessionalC = Clinic
SERUM 44-C
Advanced Amniotic Fluid Secretome
5 mL vial · Professional access
Beyond exosomes. The power of the secretome. A professional formulation built around the biological complexity of the amniotic fluid secretome — 5 billion exosomes alongside additional extracellular vesicles and naturally occurring secretome components including ECM proteins and peptides.
- 5 billion exosomes per 5 mL vial
- Amniotic fluid-derived secretome
- Beyond isolated exosomes
- Professional-use formulation
SERUM 44-C™
Advanced Amniotic Fluid Secretome
Beyond Exosomes. The Power of the Secretome.
5 Billion Exosomes · 5 mL · Professional Formulation
The Product
A sophisticated secretome formulation.
Serum 44-C™ represents a sophisticated approach to regenerative aesthetics, built around the biological complexity of the amniotic fluid secretome.
Each 5 mL vial contains 5 billion exosomes, alongside additional extracellular vesicles and other naturally occurring secretome components.
Unlike formulations focused exclusively on isolated exosomes, Serum 44-C™ embraces the broader spectrum of biological signaling molecules found within the secretome.
These components participate in cellular communication and tissue homeostasis, representing an exciting area of research in regenerative science.
Serum 44-C™ brings this scientific approach into a premium formulation developed for professional aesthetic settings.
The Science
More than exosomes. A complete signaling environment.
Exosomes are only one part of the complex communication system found within the human body.
The amniotic fluid secretome contains a diverse population of extracellular vesicles and soluble biological mediators, including proteins and signaling factors involved in intercellular communication.
Rather than focusing exclusively on exosome isolation, Serum 44-C™ is designed around the broader biological composition of the secretome.
This distinction reflects HydroKarma's philosophy: regenerative science should consider the complexity of biological signaling rather than relying on a single component.
Professional Application
Developed for advanced aesthetic practices.
Serum 44-C™ is being investigated for professional aesthetic applications, including its potential compatibility with traditional microneedling and radiofrequency microneedling technologies such as Morpheus8.
Its proposed use involves topical application during the early post-procedure period.
Specific application protocols, including timing, compatibility, and safety following procedures that disrupt the skin barrier, require appropriate validation before clinical directions can be established.
Product Highlights
The attributes of a differentiated formulation.
5 Billion Exosomes
Contained within each 5 mL vial.
Amniotic Fluid-Derived
Sourced from human perinatal biological material.
Beyond Exosomes
Contains additional extracellular vesicles and secretome components.
Professional Formulation
Developed for advanced aesthetic settings.
The Future
The future of regenerative aesthetics is more than exosomes.
At HydroKarma, we believe the future of regenerative science lies in understanding the complexity of biological communication. Serum 44-C™ reflects that philosophy by bringing together exosomes and the broader amniotic fluid secretome in one sophisticated formulation.
Beyond Exosomes. Beyond Conventional Aesthetics.
These statements have not been evaluated by the FDA. HYDROKARMA products are not intended to diagnose, treat, cure, or prevent any disease. Regenerative aesthetics support.